![]() In conclusion, pro-/synbiotic administration can be considered as a BDNF enhancer and a possible brain booster. Moreover, subgroup analysis showed that the target population, ethnicity and the mean age of participants, the number and type of probiotic strains, administration form, and the dose and duration of pro-/synbiotic supplementation were the potential sources of heterogeneity between RCTs. The meta-analysis revealed that supplementation with pro-/synbiotics significantly increased BDNF concentrations in comparison with the placebo (WMD: 0.20 ng mL −1, 95% CI: 0.06 to 0.34, I 2 = 86.6%). Our webinar on the Importance of Labor Categories for Government Contracts is TOMORROW, August 9 at 1:00 PM EST. ![]() In the present study, 10 RCTs with 12 treatment arms consisting of 652 participants were included. The weighted mean difference (WMD) and 95% confidence interval (CI) were computed for BDNF using a random-effects model. Scopus, Medline, Web of Science, Cochrane Library, and Google Scholar were searched up to Jto find eligible RCTs. Therefore, we aimed to conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to investigate the impact of pro-/synbiotic supplementation on BDNF levels. Nevertheless, the results obtained from human studies are inconsistent and conflicting. ![]() #Thebrain pro proAnimal studies have reported that pro-/synbiotic administration can increase the brain-derived neurotrophic factor (BDNF), a key regulator of neuronal function. Activate TheBrain Pro Activating TheBrain Pro To activate TheBrain Pro features: Make sure you are logged in using the same account you purchased with (by clicking on the person icon in the top right corner of the window). There is growing interest in supplementation with pro-/synbiotics for brain and mental health. Combined with WhatsApps ubiquity, ease of use and the ability to send voice messages, photos, and video messages, and conduct group chats, this makes for a robust and fully encrypted mobile. ![]()
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